| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
CXCR5 Positive Control for STJ500664 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:500 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
CXCR5 |
| Gene ID: |
643 |
| Uniprot ID: |
CXCR5_HUMAN |
| Specificity: |
This is positive control is recommended for use in combination with CXCR5 antibody STJ500664. |
| Tissue Specificity | Expression in mature B-cells and Burkitt lymphoma cells. |
| Function | Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. |
| Peptide Name | C-X-C Chemokine Receptor Type 5Cxc-R5Cxcr-5Burkitt Lymphoma Receptor 1Monocyte-Derived Receptor 15Mdr-15Cd Antigen Cd185 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | C-X-C Chemokine Receptor Type 5 proteinCxc-R5 proteinCxcr-5 proteinBurkitt Lymphoma Receptor 1 proteinMonocyte-Derived Receptor 15 proteinMdr-15 proteinCd Antigen Cd185 proteinCXCR5 proteinBLR1 proteinMDR15 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
