CXCR2 Positive Control for STJ500651 peptide (STJ505898)

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STJ505898-5
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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : CXCR2 Positive Control for STJ500651 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Cxcr2
Gene ID: 12765
Uniprot ID: CXCR2_MOUSE
Specificity: This is positive control is recommended for use in combination with CXCR2 antibody STJ500651.
Post Translational Modifications Phosphorylated upon ligand binding.which is required for desensitization.
Function Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Peptide Name C-X-C Chemokine Receptor Type 2
Cxc-R2
Cxcr-2
Gro/Mgsa Receptor
High Affinity Interleukin-8 Receptor B
Il-8r B
Cd Antigen Cd182
Database Links Reactome: R-MMU-380108
Reactome: -MMU-418594
Reactome: -MMU-6798695
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Peptide Names C-X-C Chemokine Receptor Type 2 protein
Cxc-R2 protein
Cxcr-2 protein
Gro/Mgsa Receptor protein
High Affinity Interleukin-8 Receptor B protein
Il-8r B protein
Cd Antigen Cd182 protein
Cxcr2 protein
Cmkar2 protein
Gpcr16 protein
Il8rb protein

Information sourced from Uniprot.org

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