| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | CXCR1 Positive Control for STJ500639 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: | WB: 1:500 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Cxcr1 |
| Gene ID: | 227288 |
| Uniprot ID: | CXCR1_MOUSE |
| Specificity: | This is positive control is recommended for use in combination with CXCR1 antibody STJ500639. |
| Function | Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. |
| Peptide Name | C-X-C Chemokine Receptor Type 1Cxc-R1Cxcr-1High Affinity Interleukin-8 Receptor AIl-8r ACd Antigen Cd181 |
| Database Links | Reactome: R-MMU-380108Reactome: -MMU-418594Reactome: -MMU-6798695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | C-X-C Chemokine Receptor Type 1 proteinCxc-R1 proteinCxcr-1 proteinHigh Affinity Interleukin-8 Receptor A proteinIl-8r A proteinCd Antigen Cd181 proteinCxcr1 proteinIl8ra protein |
Information sourced from Uniprot.org