Tissue Specificity | Highly expressed in heart, liver, skeletal muscle, pancreas, adrenal medulla and cortex, thyroid, testis, spleen, appendix, peripheral blood lymphocytes and bone marrow. Lower expression found in brain, placenta, lung, kidney, ovary, small intestine, stomach, lymph node, thymus and fetal liver. Expression is up-regulated in dorsolateral prefrontal cortex of patients with schizophrenia (postmortem brain study). |
Function | Involved in the selective transport and maturation of TGF-alpha family proteins. |
Peptide Name | Protein Cornichon Homolog 1Cnih-1Cornichon Family Ampa Receptor Auxiliary Protein 1Protein Cornichon HomologT-Cell Growth-Associated Molecule 77Tgam77 |
Database Links | Reactome: R-HSA-204005Reactome: R-HSA-5694530 |
Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinGolgi Apparatus MembraneLocated Primarily In The ErMay Cycle Between The Er And The Golgi Apparatus |
Alternative Peptide Names | Protein Cornichon Homolog 1 proteinCnih-1 proteinCornichon Family Ampa Receptor Auxiliary Protein 1 proteinProtein Cornichon Homolog proteinT-Cell Growth-Associated Molecule 77 proteinTgam77 proteinCNIH1 proteinCNIH proteinCNIL proteinUNQ155 proteinPRO181 protein |
Information sourced from Uniprot.org