Applications: | Immunodepletion/Immunocompetition |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Phospho-Chimaerin beta 2 Blocking Peptide is synthetically produced from the sequence and is suitable for use in western blot applications. |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | CHN1 |
Gene ID: | 1123 |
Uniprot ID: | CHIN_HUMAN |
Immunogen: | Phosphorylated synthetic peptide corresponding to unique amino acid sequence on beta 2 Chimaerin protein. |
Tissue Specificity | In neurons in brain regions that are involved in learning and memory processes. |
Post Translational Modifications | Phosphorylated. Phosphorylation is EPHA4 kinase activity-dependent. |
Function | GTPase-activating protein for p21-rac and a phorbol ester receptor. Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance. |
Peptide Name | N-Chimaerin A-Chimaerin Alpha-Chimerin N-Chimerin Nc Rho Gtpase-Activating Protein 2 |
Database Links | Reactome: R-HSA-9013148 Reactome: R-HSA-9013149 |
Alternative Peptide Names | N-Chimaerin protein A-Chimaerin protein Alpha-Chimerin protein N-Chimerin protein Nc protein Rho Gtpase-Activating Protein 2 protein CHN1 protein ARHGAP2 protein CHN protein |
Information sourced from Uniprot.org