Applications: |
WB |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Chimaerin alpha 2 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
Dilution Range: |
WB: 1:500 |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Tissue Specificity | In neurons in brain regions that are involved in learning and memory processes. |
Post Translational Modifications | Phosphorylated. Phosphorylation is EPHA4 kinase activity-dependent. |
Function | GTPase-activating protein for p21-rac and a phorbol ester receptor. Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance. |
Peptide Name | N-ChimaerinA-ChimaerinAlpha-ChimerinN-ChimerinNcRho Gtpase-Activating Protein 2 |
Database Links | Reactome: R-HSA-9013148Reactome: R-HSA-9013149 |
Alternative Peptide Names | N-Chimaerin proteinA-Chimaerin proteinAlpha-Chimerin proteinN-Chimerin proteinNc proteinRho Gtpase-Activating Protein 2 proteinCHN1 proteinARHGAP2 proteinCHN protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance