Applications: | Immunodepletion/Immunocompetition |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Chimaerin alpha 2 Blocking Peptide is synthetically produced from the sequence and is suitable for use in western blot applications. |
Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | CHN1 |
Gene ID: | 1123 |
Uniprot ID: | CHIN_HUMAN |
Immunogen: | Synthetic peptide corresponding to unique amino acid sequence on alpha 2 Chimaerin protein. |
Tissue Specificity | In neurons in brain regions that are involved in learning and memory processes. |
Post Translational Modifications | Phosphorylated. Phosphorylation is EPHA4 kinase activity-dependent. |
Function | GTPase-activating protein for p21-rac and a phorbol ester receptor. Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance. |
Peptide Name | N-ChimaerinA-ChimaerinAlpha-ChimerinN-ChimerinNcRho Gtpase-Activating Protein 2 |
Database Links | Reactome: R-HSA-9013148Reactome: R-HSA-9013149 |
Alternative Peptide Names | N-Chimaerin proteinA-Chimaerin proteinAlpha-Chimerin proteinN-Chimerin proteinNc proteinRho Gtpase-Activating Protein 2 proteinCHN1 proteinARHGAP2 proteinCHN protein |
Information sourced from Uniprot.org