CGRP Positive Control for STJ506114 peptide (STJ505839)

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STJ505839-5
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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : CGRP Positive Control for STJ506114 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500-1:5, 000
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Calca
Gene ID: 12310
Uniprot ID: CALCA_MOUSE
Specificity: This is positive control is recommended for use in combination with CGRP antibody STJ506114.
Tissue Specificity Detected in nerve cells of cerebrum, hippocampus and pons/midbrain in newborns, and only in nerve cells of pons/midbrain in adult.
Function CGRP1/CALCA is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex. Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. CGRP1 can also bind and activate CALCR-RAMP1 (AMYR1) receptor complex.
Peptide Name Calcitonin Gene-Related Peptide 1
Cgrp1
Alpha-Type Cgrp
Calcitonin Gene-Related Peptide I
Cgrp-I
Database Links
Reactome: R-MMU-418555
Reactome: -MMU-419812
Cellular Localisation Secreted
Alternative Peptide Names Calcitonin Gene-Related Peptide 1 protein
Cgrp1 protein
Alpha-Type Cgrp protein
Calcitonin Gene-Related Peptide I protein
Cgrp-I protein
Calca protein
Calc protein

Information sourced from Uniprot.org

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