CDNF protein (STJP000138)

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STJP000138
£352.50 - £1,132.50
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Short Description :CDNF-protein was developed from. For use in research applications.
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/ml
Purification:Purified by ion-exchange chromatography and gel-filtration from serum-free CHO growth media. Protein is sterile-filtrated through 0.22 µm filter
Formulation:PBS pH 7.4
Storage Instruction:Store at-70°C upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles
Gene Symbol:CDNF
Gene ID:441549
Uniprot ID:CDNF_HUMAN
Tissue Specificity Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum.
Function Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra.
Protein Name Cerebral Dopamine Neurotrophic Factor
Armet-Like Protein 1
Conserved Dopamine Neurotrophic Factor
Database Links
Cellular Localisation Secreted
Alternative Protein Names Cerebral Dopamine Neurotrophic Factor protein
Armet-Like Protein 1 protein
Conserved Dopamine Neurotrophic Factor protein
CDNF protein
ARMETL1 protein

Information sourced from Uniprot.org

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