CDNF protein (STJP000138)

SKU:
STJP000138
£352.50 - £1,119.50
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Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : CDNF-protein was developed from. For use in research applications.
Formulation: PBS pH 7.4
Purification: Purified by ion-exchange chromatography and gel-filtration from serum-free CHO growth media. Protein is sterile-filtrated through 0.22 µm filter
Concentration: 1 mg/ml
Storage Instruction: Store at-70°C upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles
Gene Symbol: CDNF
Gene ID: 441549
Uniprot ID: CDNF_HUMAN
Tissue Specificity Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum.
Function Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra.
Protein Name Cerebral Dopamine Neurotrophic Factor
Armet-Like Protein 1
Conserved Dopamine Neurotrophic Factor
Cellular Localisation Secreted
Alternative Protein Names Cerebral Dopamine Neurotrophic Factor protein
Armet-Like Protein 1 protein
Conserved Dopamine Neurotrophic Factor protein
CDNF protein
ARMETL1 protein

Information sourced from Uniprot.org

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