CD68 Positive Control for STJ500480 peptide (STJ505606)

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STJ505606-5
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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : CD68 Positive Control for STJ500480 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:2, 500-1:5, 000
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Cd68
Gene ID: 12514
Uniprot ID: CD68_MOUSE
Specificity: This is positive control is recommended for use in combination with CD68 antibody STJ500480.
Immunogen: Purified Protein
Tissue Specificity Expressed in tissue macrophages and to a lesser extent in dendritic cells.
Post Translational Modifications N- and O-glycosylated.
Function Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Peptide Name Macrosialin
Cd Antigen Cd68
Database Links Reactome: R-MMU-6798695
Cellular Localisation Isoform Long: Endosome Membrane
Single-Pass Type I Membrane Protein
Lysosome Membrane
Isoform Short: Cell Membrane
Alternative Peptide Names Macrosialin protein
Cd Antigen Cd68 protein
Cd68 protein

Information sourced from Uniprot.org

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