Tissue Specificity | In eosinophils as well as trace amounts in neutrophils and monocytes. |
Function | Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. (Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection. |
Peptide Name | C-C Chemokine Receptor Type 3C C Ckr3C-C Ckr-3Cc-Ckr-3Ccr-3Ccr3Ckr 3Ckr3Eosinophil Eotaxin ReceptorCd Antigen Cd193 |
Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Peptide Names | C-C Chemokine Receptor Type 3 proteinC C Ckr3 proteinC-C Ckr-3 proteinCc-Ckr-3 proteinCcr-3 proteinCcr3 proteinCkr 3 proteinCkr3 proteinEosinophil Eotaxin Receptor proteinCd Antigen Cd193 proteinCCR3 proteinCMKBR3 protein |
Information sourced from Uniprot.org