Applications: |
Immunodepletion/Immunocompetition |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
CCR3 Blocking Peptide is synthetically produced from the 1-50 aa sequence and is suitable for use in western blot applications. |
Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
CCR3 |
Gene ID: |
1232 |
Uniprot ID: |
CCR3_HUMAN |
Immunogen Region: |
1-50 aa |
Immunogen: |
Synthetic peptide taken within amino acid region 1-50 on human CCR3 protein. |
Tissue Specificity | In eosinophils as well as trace amounts in neutrophils and monocytes. |
Function | Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. (Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection. |
Peptide Name | C-C Chemokine Receptor Type 3C C Ckr3C-C Ckr-3Cc-Ckr-3Ccr-3Ccr3Ckr 3Ckr3Eosinophil Eotaxin ReceptorCd Antigen Cd193 |
Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Peptide Names | C-C Chemokine Receptor Type 3 proteinC C Ckr3 proteinC-C Ckr-3 proteinCc-Ckr-3 proteinCcr-3 proteinCcr3 proteinCkr 3 proteinCkr3 proteinEosinophil Eotaxin Receptor proteinCd Antigen Cd193 proteinCCR3 proteinCMKBR3 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance