Applications: |
WB |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
CCR1 Positive Control for STJ500394 is synthetically produced from the sequence and is suitable for use in western blot applications. |
Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
Dilution Range: |
WB: 1:500 |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
CCR1 |
Gene ID: |
1230 |
Uniprot ID: |
CCR1_HUMAN |
Specificity: |
This is positive control is recommended for use in combination with CCR1 antibody STJ500394. |
Tissue Specificity | Widely expressed in different hematopoietic cells. |
Function | Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation. |
Peptide Name | C-C Chemokine Receptor Type 1C-C Ckr-1Cc-Ckr-1Ccr-1Ccr1Hm145Ld78 ReceptorMacrophage Inflammatory Protein 1-Alpha ReceptorMip-1alpha-RRantes-RCd Antigen Cd191 |
Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6783783 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Peptide Names | C-C Chemokine Receptor Type 1 proteinC-C Ckr-1 proteinCc-Ckr-1 proteinCcr-1 proteinCcr1 proteinHm145 proteinLd78 Receptor proteinMacrophage Inflammatory Protein 1-Alpha Receptor proteinMip-1alpha-R proteinRantes-R proteinCd Antigen Cd191 proteinCCR1 proteinCMKBR1 proteinCMKR1 proteinSCYAR1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance