C15orf42 Positive Control peptide (STJ505237)

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STJ505237-5
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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : C15orf42 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: TICRR
Gene ID: 90381
Uniprot ID: TICRR_HUMAN
Function Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC). Required to prevent mitotic entry after treatment with ionizing radiation.
Peptide Name Treslin
Topbp1-Interacting Checkpoint And Replication Regulator
Topbp1-Interacting - Replication-Stimulating Protein
Cellular Localisation Nucleus
Associates With Chromatin
Alternative Peptide Names Treslin protein
Topbp1-Interacting Checkpoint And Replication Regulator protein
Topbp1-Interacting - Replication-Stimulating Protein protein
TICRR protein
C15orf42 protein

Information sourced from Uniprot.org

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