BTB/POZ domain-containing protein 7 Positive Control peptide (STJ503752)
SPECIFICATIONS
General Information
| Short Description | BTB/POZ domain-containing protein 7 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | WB: 1:500 |
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | BTBD7 |
| Gene ID | 55727 |
| Uniprot ID | BTBD7_HUMAN |
Additional Info
| Function | Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression. |
| Peptide Name | Btb/Poz Domain-Containing Protein 7 |
| Cellular Localisation | Nucleus |
| Alternative Peptide Names | Btb/Poz Domain-Containing Protein 7 proteinBTBD7 proteinKIAA1525 protein |
Information sourced from Uniprot.org