| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | BTB/POZ domain-containing protein 7 Blocking Peptide is synthetically produced from the 1050-1150 sequence and is suitable for use in western blot applications. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | BTBD7 |
| Gene ID: | 55727 |
| Uniprot ID: | BTBD7_HUMAN |
| Immunogen Region: | 1050-1150 |
| Immunogen: | Synthetic peptide taken within amino acid region 1050-1150 on human BTBD7 protein. |
| Function | Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression. |
| Peptide Name | Btb/Poz Domain-Containing Protein 7 |
| Cellular Localisation | Nucleus |
| Alternative Peptide Names | Btb/Poz Domain-Containing Protein 7 proteinBTBD7 proteinKIAA1525 protein |
Information sourced from Uniprot.org