| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Bone marrow stromal cell antigen 1 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:500 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Tissue Specificity | Expressed in various tissues including placenta, lung, liver and kidney. |
| Function | Catalyzes both the synthesis of cyclic ADP-beta-D-ribose (cADPR) from NAD(+), and its hydrolysis to ADP-D-ribose (ADPR). Cyclic ADPR is known to serve as an endogenous second messenger that elicits calcium release from intracellular stores, and thus regulates the mobilization of intracellular calcium (Probable). May be involved in pre-B-cell growth (Probable). |
| Peptide Name | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 2Adp-Ribosyl Cyclase 2Bone Marrow Stromal Cell Antigen 1Bst-1Cyclic Adp-Ribose Hydrolase 2Cadpr Hydrolase 2Cd Antigen Cd157 |
| Database Links | Reactome: R-HSA-163125Reactome: R-HSA-196807Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Peptide Names | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 2 proteinAdp-Ribosyl Cyclase 2 proteinBone Marrow Stromal Cell Antigen 1 proteinBst-1 proteinCyclic Adp-Ribose Hydrolase 2 proteinCadpr Hydrolase 2 proteinCd Antigen Cd157 proteinBST1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
