| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
BCKDH Blocking Peptide is synthetically produced from the 170-200 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
BCKDK |
| Gene ID: |
10295 |
| Uniprot ID: |
BCKD_HUMAN |
| Immunogen Region: |
170-200 |
| Immunogen: |
Synthetic peptide taken within amino acid region 170-200 on human BCKD protein. |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Autophosphorylated. |
| Function | Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex. |
| Peptide Name | 3-Methyl-2-Oxobutanoate Dehydrogenase Lipoamide Kinase - MitochondrialBranched-Chain Alpha-Ketoacid Dehydrogenase KinaseBckd-KinaseBckdhkin |
| Database Links | Reactome: R-HSA-70895 |
| Cellular Localisation | Mitochondrion MatrixMitochondrion |
| Alternative Peptide Names | 3-Methyl-2-Oxobutanoate Dehydrogenase Lipoamide Kinase - Mitochondrial proteinBranched-Chain Alpha-Ketoacid Dehydrogenase Kinase proteinBckd-Kinase proteinBckdhkin proteinBCKDK protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
