Tissue Specificity | Widely expressed. Highest levels are found in adult brain and skeletal muscle. Lower levels are found in heart and kidney. |
Function | Acts as a guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases. |
Peptide Name | Rho Guanine Nucleotide Exchange Factor 3Exchange Factor Found In Platelets And Leukemic And Neuronal TissuesXpln |
Database Links | Reactome: R-HSA-193648Reactome: R-HSA-416482Reactome: R-HSA-8980692Reactome: R-HSA-9013026 |
Cellular Localisation | Cytoplasm |
Alternative Peptide Names | Rho Guanine Nucleotide Exchange Factor 3 proteinExchange Factor Found In Platelets And Leukemic And Neuronal Tissues proteinXpln proteinARHGEF3 protein |
Information sourced from Uniprot.org