| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Aquaporin 1 Blocking Peptide is synthetically produced from the 215-265 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
AQP1 |
| Gene ID: |
358 |
| Uniprot ID: |
AQP1_HUMAN |
| Immunogen Region: |
215-265 |
| Immunogen: |
Synthetic peptide taken within amino acid region 215-265 on human Aquaporin 1 protein. |
| Tissue Specificity | Detected in erythrocytes (at protein level). Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver. |
| Function | Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane. |
| Peptide Name | Aquaporin-1Aqp-1Aquaporin-ChipUrine Water ChannelWater Channel Protein For Red Blood Cells And Kidney Proximal Tubule |
| Database Links | Reactome: R-HSA-1237044Reactome: R-HSA-1247673Reactome: R-HSA-432040Reactome: R-HSA-432047 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Aquaporin-1 proteinAqp-1 proteinAquaporin-Chip proteinUrine Water Channel proteinWater Channel Protein For Red Blood Cells And Kidney Proximal Tubule proteinAQP1 proteinCHIP28 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
