| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ZYX |
| Gene ID: | 7791 |
| Uniprot ID: | ZYX_HUMAN |
| Immunogen Region: | 350-572 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-572 of human Zyxinin (NP_003452.1). |
| Immunogen Sequence: | PLTLKEVEELEQLTQQLMQD MEHPQRQNVAVNELCGRCHQ PLARAQPAVRALGQLFHIAC FTCHQCAQQLQGQQFYSLEG APYCEGCYTDTLEKCNTCGE PITDRMLRATGKAYHPHCFT CVVCARPLEGTSFIVDQANR PHCVPDYHKQYAPRCSVCSE PIMPEPGRDETVRVVALDKN FHMKCYKCEDCGKPLSIEAD DNGCFPLDGHVLCRKCHTAR AQT |
| Function | Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression. |
| Protein Name | ZyxinZyxin-2 |
| Cellular Localisation | CytoplasmCytoskeletonNucleusCell JunctionFocal AdhesionAssociates With The Actin Cytoskeleton Near The Adhesion PlaquesEnters The Nucleus In The Presence Of Hesx1 |
| Alternative Antibody Names | Anti-Zyxin antibodyAnti-Zyxin-2 antibodyAnti-ZYX antibody |
Information sourced from Uniprot.org