| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Zona pellucida sperm-binding protein 4 (231-280 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ZP4 |
| Gene ID: | 57829 |
| Uniprot ID: | ZP4_HUMAN |
| Immunogen Region: | 231-280 aa |
| Specificity: | ZP4 Polyclonal Antibody detects endogenous levels of ZP4 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ZP4 at the amino acid range 231-280 |
| Post Translational Modifications | Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida. |
| Function | Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor. |
| Protein Name | Zona Pellucida Sperm-Binding Protein 4Zona Pellucida Glycoprotein 4Zp-4Zona Pellucida Protein B Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 4 |
| Database Links | Reactome: R-HSA-2534343 |
| Cellular Localisation | Processed Zona Pellucida Sperm-Binding Protein 4: Zona PellucidaCell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Zona Pellucida Sperm-Binding Protein 4 antibodyAnti-Zona Pellucida Glycoprotein 4 antibodyAnti-Zp-4 antibodyAnti-Zona Pellucida Protein B Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 4 antibodyAnti-ZP4 antibodyAnti-ZPB antibody |
Information sourced from Uniprot.org
