Anti-ZNF521 antibody (997-1047 aa) (STJ195536)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ZN521 at the amino acid range 997-1047
General Information
| Short Description | Rabbit polyclonal anti-Zinc finger protein 521 (997-1047 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ZNF521 |
| Gene ID | 25925 |
| Uniprot ID | ZN521_HUMAN |
| Immunogen | Synthesized peptide derived from the human ZN521 at the amino acid range 997-1047 |
| Immunogen Region | 997-1047 aa |
| Specificity | This antibody detects endogenous levels of ZN521 at Human/Mouse |
Additional Info
| Function | Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage.this interaction preventing EBF1 to bind DNA and activate target genes. |
| Protein Name | Zinc Finger Protein 521Early Hematopoietic Zinc Finger ProteinLyst-Interacting Protein 3 |
| Database Links | Reactome: R-HSA-8940973Reactome: R-HSA-9823739Reactome: R-HSA-9832991 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Zinc Finger Protein 521 antibodyAnti-Early Hematopoietic Zinc Finger Protein antibodyAnti-Lyst-Interacting Protein 3 antibodyAnti-ZNF521 antibodyAnti-EHZF antibodyAnti-LIP3 antibody |
Information sourced from Uniprot.org