| Short Description : | Rabbit monoclonal ZNF24 (160-242 aa) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | SRM5183 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Gene Symbol: | ZNF24 |
| Gene ID: | 7572 |
| Uniprot ID: | ZNF24_HUMAN |
| Immunogen Region: | 160-242 aa |
| Immunogen Sequence: | EAQGLPSSELDAVENQLKWA SWELHSLRHCDDDGRTENGA LAPKQELPSALESHEVPGTL NMGVPQIFKYGETCFPKGRF ERK |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 160-242 of human ZNF24 (NP_110378.3). |
| Tissue Specificity | Expressed in many tissues except in heart. |
| Post Translational Modifications | Sumoylated. |
| Function | Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence. Has transcription repressor activity in vitro. |
| Protein Name | Zinc Finger Protein 24Retinoic Acid Suppression Protein ARsg-AZinc Finger And Scan Domain-Containing Protein 3Zinc Finger Protein 191Zinc Finger Protein Kox17 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Zinc Finger Protein 24 antibodyAnti-Retinoic Acid Suppression Protein A antibodyAnti-Rsg-A antibodyAnti-Zinc Finger And Scan Domain-Containing Protein 3 antibodyAnti-Zinc Finger Protein 191 antibodyAnti-Zinc Finger Protein Kox17 antibodyAnti-ZNF24 antibodyAnti-KOX17 antibodyAnti-ZNF191 antibodyAnti-ZSCAN3 antibody |
Information sourced from Uniprot.org
