| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ZNF143 |
| Gene ID: | 7702 |
| Uniprot ID: | ZN143_HUMAN |
| Immunogen Region: | 437-638 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 437-638 of human ZNF143 (NP_003433.3). |
| Immunogen Sequence: | RTAHNDTEPIEEEQEAFFEP PPGQGEDVLKGSQITYVTGV EGDDVVSTQVATVTQSGLSQ QVTLISQDGTQHVNISQADM QAIGNTITMVTQDGTPITVP AHDAVISSAGTHSVAMVTAE GTEGEQVAIVAQDLAAFHTA SSEMGHQQHSHHLVTTETRP LTLVATSNGTQIAVQLGEQP SLEEAIRIASRIQQGETPGL DD |
| Tissue Specificity | Expressed in all tissues tested, with the strongest expression in ovary. |
| Function | Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8. |
| Protein Name | Zinc Finger Protein 143 Sph-Binding Factor Selenocysteine Trna Gene Transcription-Activating Factor Hstaf |
| Database Links | Reactome: R-HSA-6807505 Reactome: R-HSA-749476 Reactome: R-HSA-76071 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Zinc Finger Protein 143 antibody Anti-Sph-Binding Factor antibody Anti-Selenocysteine Trna Gene Transcription-Activating Factor antibody Anti-Hstaf antibody Anti-ZNF143 antibody Anti-SBF antibody Anti-STAF antibody |
Information sourced from Uniprot.org