| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ZNF143 (437-638) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ZNF143 |
| Gene ID: |
7702 |
| Uniprot ID: |
ZN143_HUMAN |
| Immunogen Region: |
437-638 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 437-638 of human ZNF143 (NP_003433.3). |
| Immunogen Sequence: |
RTAHNDTEPIEEEQEAFFEP PPGQGEDVLKGSQITYVTGV EGDDVVSTQVATVTQSGLSQ QVTLISQDGTQHVNISQADM QAIGNTITMVTQDGTPITVP AHDAVISSAGTHSVAMVTAE GTEGEQVAIVAQDLAAFHTA SSEMGHQQHSHHLVTTETRP LTLVATSNGTQIAVQLGEQP SLEEAIRIASRIQQGETPGL DD |
| Tissue Specificity | Expressed in all tissues tested, with the strongest expression in ovary. |
| Function | Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8. |
| Protein Name | Zinc Finger Protein 143Sph-Binding FactorSelenocysteine Trna Gene Transcription-Activating FactorHstaf |
| Database Links | Reactome: R-HSA-6807505Reactome: R-HSA-749476Reactome: R-HSA-76071 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Zinc Finger Protein 143 antibodyAnti-Sph-Binding Factor antibodyAnti-Selenocysteine Trna Gene Transcription-Activating Factor antibodyAnti-Hstaf antibodyAnti-ZNF143 antibodyAnti-SBF antibodyAnti-STAF antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
