Anti-ZNF131 antibody (274-324 aa) (STJ195263)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ZN131 at the amino acid range 274-324
General Information
| Short Description | Rabbit polyclonal anti-Zinc finger protein 131 (274-324 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ZNF131 |
| Gene ID | 7690 |
| Uniprot ID | ZN131_HUMAN |
| Immunogen | Synthesized peptide derived from the human ZN131 at the amino acid range 274-324 |
| Immunogen Region | 274-324 aa |
| Specificity | This antibody detects endogenous levels of ZN131 at Human/Mouse |
Additional Info
| Post Translational Modifications | Monosumoylated at Lys-601 by CBX4 and UHRF2. Sumoylation may potentiate ZNF131 inhibition of estrogen signaling. Sumoylation does not interfere with ubiquitination. Ubiquitinated. |
| Function | Plays a role during development and organogenesis as well as in the function of the adult central nervous system. May be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling. |
| Protein Name | Zinc Finger Protein 131 |
| Database Links | Reactome: R-HSA-3899300 |
| Cellular Localisation | NucleusSumoylation Does Not Affect Nuclear Localization |
| Alternative Antibody Names | Anti-Zinc Finger Protein 131 antibodyAnti-ZNF131 antibody |
Information sourced from Uniprot.org