| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Zinc finger protein 131 (274-324 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ZNF131 |
| Gene ID: | 7690 |
| Uniprot ID: | ZN131_HUMAN |
| Immunogen Region: | 274-324 aa |
| Specificity: | This antibody detects endogenous levels of ZN131 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human ZN131 at the amino acid range 274-324 |
| Post Translational Modifications | Monosumoylated at Lys-601 by CBX4 and UHRF2. Sumoylation may potentiate ZNF131 inhibition of estrogen signaling. Sumoylation does not interfere with ubiquitination. Ubiquitinated. |
| Function | Plays a role during development and organogenesis as well as in the function of the adult central nervous system. May be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling. |
| Protein Name | Zinc Finger Protein 131 |
| Database Links | Reactome: R-HSA-3899300 |
| Cellular Localisation | NucleusSumoylation Does Not Affect Nuclear Localization |
| Alternative Antibody Names | Anti-Zinc Finger Protein 131 antibodyAnti-ZNF131 antibody |
Information sourced from Uniprot.org