• Western blot with Anti-ZMPSTE24 Antibody (STJ503598) with 1) SKNBE cells, 2) ZMPSTE24 peptide. Antibody at 1:500 dilution in buffer.

Anti-ZMPSTE24 antibody (450-480) (STJ503598)

SKU:
STJ503598-100

€551.88
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Host: Rabbit
Applications: ELISA/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ZMPSTE24 (450-480) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.55 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: ZMPSTE24
Gene ID: 10269
Uniprot ID: FACE1_HUMAN
Immunogen Region: 450-480
Immunogen: Synthetic peptide taken within amino acid region 450-480 on mouse ZMPSTE24 protein.
Tissue Specificity Widely expressed. High levels in kidney, prostate, testis and ovary.
Function Transmembrane metalloprotease whose catalytic activity is critical for processing lamin A/LMNA on the inner nuclear membrane and clearing clogged translocons on the endoplasmic reticulum. Proteolytically removes the C-terminal three residues of farnesylated proteins. Plays also an antiviral role independently of its protease activity by restricting enveloped RNA and DNA viruses, including influenza A, Zika, Ebola, Sindbis, vesicular stomatitis, cowpox, and vaccinia. Mechanistically, controls IFITM antiviral pathway to hinder viruses from breaching the endosomal barrier by modulating membrane fluidity.
Protein Name Caax Prenyl Protease 1 Homolog
Farnesylated Proteins-Converting Enzyme 1
Face-1
Prenyl Protein-Specific Endoprotease 1
Zinc Metalloproteinase Ste24 Homolog
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Nucleus Inner Membrane
Early Endosome Membrane
Late Endosome Membrane
Alternative Antibody Names Anti-Caax Prenyl Protease 1 Homolog antibody
Anti-Farnesylated Proteins-Converting Enzyme 1 antibody
Anti-Face-1 antibody
Anti-Prenyl Protein-Specific Endoprotease 1 antibody
Anti-Zinc Metalloproteinase Ste24 Homolog antibody
Anti-ZMPSTE24 antibody
Anti-FACE1 antibody
Anti-STE24 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance