| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ZIC3 |
| Gene ID: | 7547 |
| Uniprot ID: | ZIC3_HUMAN |
| Immunogen Region: | 1-240 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ZIC3 (NP_003404.1). |
| Immunogen Sequence: | MTMLLDGGPQFPGLGVGSFG APRHHEMPNREPAGMGLNPF GDSTHAAAAAAAAAAFKLSP AAAHDLSSGQSSAFTPQGSG YANALGHHHHHHHHHHHTSQ VPSYGGAASAAFNSTREFLF RQRSSGLSEAASGGGQHGLF AGSASSLHAPAGIPEPPSYL LFPGLHEQGAGHPSPTGHVD NNQVHLGLRGELFGRADPYR PVASPRTDPYAAGAQFPNYS PMNMNMGVNVAAHHGPGAF |
| Function | Acts as a transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'. |
| Protein Name | Zinc Finger Protein Zic 3Zinc Finger Protein 203Zinc Finger Protein Of The Cerebellum 3 |
| Database Links | Reactome: R-HSA-2892247Reactome: R-HSA-452723 |
| Cellular Localisation | NucleusCytoplasmLocalizes In The Cytoplasm In Presence Of Mdfic OverexpressionTranslocation To The Nucleus Requires Kpna1 Or Kpna6 |
| Alternative Antibody Names | Anti-Zinc Finger Protein Zic 3 antibodyAnti-Zinc Finger Protein 203 antibodyAnti-Zinc Finger Protein Of The Cerebellum 3 antibodyAnti-ZIC3 antibodyAnti-ZNF203 antibody |
Information sourced from Uniprot.org