| Host: | Rabbit |
| Applications: | IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Zinc finger protein ZIC 1 and Zinc finger protein ZIC 2 and Zinc finger protein ZIC 3 and Zinc finger protein ZIC 4 and Zinc finger protein ZIC 5 (281-330 aa) is suitable for use in Immunofluorescence and ELISA researc |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IF 1:200-1:1000ELISA 1:40000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ZIC3ZIC27547754684107ZIC3_HUMANZIC2_HUMANZIC4_HUMAN |
| Immunogen Region: | 281-330 aa |
| Specificity: | Zic1/2/3/4/5 Polyclonal Antibody detects endogenous levels of Zic1/2/3/4/5 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ZIC1/2/3/4/5 at the amino acid range 281-330 |
| Function | Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Involved in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN). Plays a role in the regulation of MF axon pathway choice. Promotes MF migration towards ipsilaterally-located cerebellar territories. May have a role in shear flow mechanotransduction in osteocytes. Retains nuclear GLI1 and GLI3 in the cytoplasm. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3'. |
| Protein Name | Zinc Finger Protein Zic 1Zinc Finger Protein 201Zinc Finger Protein Of The Cerebellum 1 |
| Cellular Localisation | NucleusCytoplasmLocalizes In The Cytoplasm In Presence Of Mdfic Overexpression |
| Alternative Antibody Names | Anti-Zinc Finger Protein Zic 1 antibodyAnti-Zinc Finger Protein 201 antibodyAnti-Zinc Finger Protein Of The Cerebellum 1 antibodyAnti-ZIC1 antibodyAnti-ZIC antibodyAnti-ZNF201 antibody |
Information sourced from Uniprot.org