| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-AN1-type zinc finger protein 5 (84-134) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ZFAND5 |
| Gene ID: |
7763 |
| Uniprot ID: |
ZFAN5_HUMAN |
| Immunogen Region: |
84-134 |
| Specificity: |
This antibody detects endogenous levels of human ZFAN5 |
| Immunogen: |
Synthesized peptide derived from human ZFAN5 AA range: 84-134 |
| Function | Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation. |
| Protein Name | An1-Type Zinc Finger Protein 5Zinc Finger A20 Domain-Containing Protein 2Zinc Finger Protein 216 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-An1-Type Zinc Finger Protein 5 antibodyAnti-Zinc Finger A20 Domain-Containing Protein 2 antibodyAnti-Zinc Finger Protein 216 antibodyAnti-ZFAND5 antibodyAnti-ZA20D2 antibodyAnti-ZNF216 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
