| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human/Mouse/Rat/Dog |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-ZEB2 (545-558) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 100+38kDa bands observed in Human Liver lysates (calculated MW of 136kDa according to NP_055610.1). Recommended concentration: 0.2-0.5µg/ml. Primary incubation was 1 hour. We be |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | ZEB2 |
| Gene ID: | 9839 |
| Uniprot ID: | ZEB2_HUMAN |
| Immunogen Region: | 545-558 |
| Accession Number: | NP_055610.1; NP_001165124.1 |
| Specificity: | This antibody is expected to recognize both reported isoforms (NP_055610.1; NP_001165124.1). |
| Immunogen Sequence: | TDSRRQISNIKKEK |
| Function | Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters. Represses transcription of E-cadherin. Represses expression of MEOX2. |
| Protein Name | Zinc Finger E-Box-Binding Homeobox 2Smad-Interacting Protein 1Smadip1Zinc Finger Homeobox Protein 1b |
| Database Links | Reactome: R-HSA-9762293Reactome: R-HSA-9823739Reactome: R-HSA-9832991 |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Zinc Finger E-Box-Binding Homeobox 2 antibodyAnti-Smad-Interacting Protein 1 antibodyAnti-Smadip1 antibodyAnti-Zinc Finger Homeobox Protein 1b antibodyAnti-ZEB2 antibodyAnti-KIAA0569 antibodyAnti-SIP1 antibodyAnti-ZFHX1B antibodyAnti-ZFX1B antibodyAnti-HRIHFB2411 antibody |
Information sourced from Uniprot.org
