• Immunohistochemistry analysis of ZDHHC18 in paraffin-embedded human lung cancer using ZDHHC18 Rabbit polyclonal antibody (STJ117393) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of various lysates using ZDHHC18 Rabbit polyclonal antibody (STJ117393) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-ZDHHC18 antibody (301-388) (STJ117393)

SKU:
STJ117393

£112.50 - £524.50
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Host: Rabbit
Applications: WB/IHC-P/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IHC-P:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ZDHHC18
Gene ID: 84243
Uniprot ID: ZDH18_HUMAN
Immunogen Region: 301-388
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 301-388 of human ZDHHC18 (NP_115659.1).
Immunogen Sequence: YLVASNLTTNEDIKGSWSSK RGGEASVNPYSHKSIITNCC AVLCGPLPPSLIDRRGFVQS DTVLPSPIRSDEPACRAKPD ASMVGGHP
Tissue Specificity Widely expressed.
Function Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates, such as CGAS, HRAS and LCK. Acts as a negative regulator of the cGAS-STING pathway be mediating palmitoylation and inactivation of CGAS. May also have a palmitoyltransferase activity toward the beta-2 adrenergic receptor/ADRB2 and therefore regulate G protein-coupled receptor signaling.
Protein Name Palmitoyltransferase Zdhhc18
Dhhc Domain-Containing Cysteine-Rich Protein 18
Dhhc-18
Zinc Finger Dhhc Domain-Containing Protein 18
Cellular Localisation Golgi Apparatus Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Palmitoyltransferase Zdhhc18 antibody
Anti-Dhhc Domain-Containing Cysteine-Rich Protein 18 antibody
Anti-Dhhc-18 antibody
Anti-Zinc Finger Dhhc Domain-Containing Protein 18 antibody
Anti-ZDHHC18 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance