Anti-ZBTB49 antibody (31-81 aa) (STJ193769)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ZBT49 at the amino acid range 31-81
General Information
| Short Description | Rabbit polyclonal anti-Zinc finger and BTB domain-containing protein 49 (31-81 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ZBTB49 |
| Gene ID | 166793 |
| Uniprot ID | ZBT49_HUMAN |
| Immunogen | Synthesized peptide derived from the human ZBT49 at the amino acid range 31-81 |
| Immunogen Region | 31-81 aa |
| Specificity | This antibody detects endogenous levels of ZBT49 at Human/Mouse |
Additional Info
| Function | Transcription factor. Inhibits cell proliferation by activating either CDKN1A/p21 transcription or RB1 transcription. Isoform 1: Binds CDKN1A promoter and activates its transcription.this activity is further potentiated in the presence of EP300 (synergistic) and ZBTB17/Miz-1 (additive). Isoform 3: Activates RB1 transcription most probably by antagonizing ZBTB17 repression of RB1. Does not bind directly RB1 promoter. |
| Protein Name | Zinc Finger And Btb Domain-Containing Protein 49Zinc Finger Protein 509 |
| Database Links | |
| Cellular Localisation | Isoform 1: CytoplasmNucleusPredominantly Located In The NucleusIsoform 3: Cytoplasm |
| Alternative Antibody Names | Anti-Zinc Finger And Btb Domain-Containing Protein 49 antibodyAnti-Zinc Finger Protein 509 antibodyAnti-ZBTB49 antibodyAnti-ZNF509 antibody |
Information sourced from Uniprot.org