| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Zinc finger and BTB domain-containing protein 49 (31-81 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ZBTB49 |
| Gene ID: |
166793 |
| Uniprot ID: |
ZBT49_HUMAN |
| Immunogen Region: |
31-81 aa |
| Specificity: |
This antibody detects endogenous levels of ZBT49 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human ZBT49 at the amino acid range 31-81 |
| Function | Transcription factor. Inhibits cell proliferation by activating either CDKN1A/p21 transcription or RB1 transcription. Isoform 1: Binds CDKN1A promoter and activates its transcription.this activity is further potentiated in the presence of EP300 (synergistic) and ZBTB17/Miz-1 (additive). Isoform 3: Activates RB1 transcription most probably by antagonizing ZBTB17 repression of RB1. Does not bind directly RB1 promoter. |
| Protein Name | Zinc Finger And Btb Domain-Containing Protein 49Zinc Finger Protein 509 |
| Cellular Localisation | Isoform 1: CytoplasmNucleusPredominantly Located In The NucleusIsoform 3: Cytoplasm |
| Alternative Antibody Names | Anti-Zinc Finger And Btb Domain-Containing Protein 49 antibodyAnti-Zinc Finger Protein 509 antibodyAnti-ZBTB49 antibodyAnti-ZNF509 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
