| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Zinc finger and BTB domain-containing protein 1 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ZBTB1 |
| Gene ID: | 22890 |
| Uniprot ID: | ZBTB1_HUMAN |
| Specificity: | This antibody detects endogenous levels of ZBTB1 at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human ZBTB1 |
| Function | Acts as a transcriptional repressor. Represses cAMP-responsive element (CRE)-mediated transcriptional activation. In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis. Plays a key role in the transcriptional regulation of T lymphocyte development. |
| Protein Name | Zinc Finger And Btb Domain-Containing Protein 1 |
| Cellular Localisation | NucleusNucleoplasmLocalized In Dot-Like Structures In The NucleusColocalized With Smrt In Nuclear BodiesThe Sumoylated Form Is Preferentially Located In The Nucleoplasm Outside The Nuclear Bodies |
| Alternative Antibody Names | Anti-Zinc Finger And Btb Domain-Containing Protein 1 antibodyAnti-ZBTB1 antibodyAnti-KIAA0997 antibody |
Information sourced from Uniprot.org