| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | YY1AP1 |
| Gene ID: | 55249 |
| Uniprot ID: | YYAP1_HUMAN |
| Immunogen Region: | 1-80 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human YY1AP1 (NP_060723.2). |
| Immunogen Sequence: | MGFSNMEDDGPEEEERVAEP QANFNTPQALRFEELLANLL NEQHQIAKELFEQLKMKKPS AKQQKEVEKVKPQCKEVHQT |
| Tissue Specificity | Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart. Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas. |
| Function | Associates with the INO80 chromatin remodeling complex, which is responsible for transcriptional regulation, DNA repair, and replication. Enhances transcription activation by YY1. Plays a role in cell cycle regulation. |
| Protein Name | Yy1-Associated Protein 1Hepatocellular Carcinoma Susceptibility ProteinHepatocellular Carcinoma-Associated Protein 2 |
| Cellular Localisation | CytoplasmNucleusNucleoplasmNucleolus |
| Alternative Antibody Names | Anti-Yy1-Associated Protein 1 antibodyAnti-Hepatocellular Carcinoma Susceptibility Protein antibodyAnti-Hepatocellular Carcinoma-Associated Protein 2 antibodyAnti-YY1AP1 antibodyAnti-HCCA2 antibodyAnti-YY1AP antibody |
Information sourced from Uniprot.org