| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | YPEL5 |
| Gene ID: | 51646 |
| Uniprot ID: | YPEL5_HUMAN |
| Immunogen Region: | 1-121 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-121 of human YPEL5 (NP_057145.1). |
| Immunogen Sequence: | MGRIFLDHIGGTRLFSCANC DTILTNRSELISTRFTGATG RAFLFNKVVNLQYSEVQDRV MLTGRHMVRDVSCKNCNSKL GWIYEFATEDSQRYKEGRVI LERALVRESEGFEEHVPSDN S |
| Function | Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Required for normal cell proliferation. |
| Protein Name | Protein Yippee-Like 5 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeSpindle PoleMidbodyDeteted In Nucleus And At The Centrosome During InterphaseDuring MitosisDetected On The Mitotic SpindleAt Spindle Poles And At The Midbody |
| Alternative Antibody Names | Anti-Protein Yippee-Like 5 antibodyAnti-YPEL5 antibodyAnti-CGI-127 antibody |
Information sourced from Uniprot.org