Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-YPEL5 (1-121) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
YPEL5 |
Gene ID: |
51646 |
Uniprot ID: |
YPEL5_HUMAN |
Immunogen Region: |
1-121 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-121 of human YPEL5 (NP_057145.1). |
Immunogen Sequence: |
MGRIFLDHIGGTRLFSCANC DTILTNRSELISTRFTGATG RAFLFNKVVNLQYSEVQDRV MLTGRHMVRDVSCKNCNSKL GWIYEFATEDSQRYKEGRVI LERALVRESEGFEEHVPSDN S |
Function | Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Required for normal cell proliferation. |
Protein Name | Protein Yippee-Like 5 |
Database Links | Reactome: R-HSA-6798695 |
Cellular Localisation | NucleusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeSpindle PoleMidbodyDeteted In Nucleus And At The Centrosome During InterphaseDuring MitosisDetected On The Mitotic SpindleAt Spindle Poles And At The Midbody |
Alternative Antibody Names | Anti-Protein Yippee-Like 5 antibodyAnti-YPEL5 antibodyAnti-CGI-127 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance