Anti-YEATS2 antibody (130-331) (STJ11101464)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal YEATS2 (130-331) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | YEATS2 |
| Gene ID | 55689 |
| Uniprot ID | YETS2_HUMAN |
| Immunogen Region | 130-331 |
| Immunogen Sequence | AETPSANHSESDSLSQHNDF LSDKDNNSNMDIEERLSNNM EQRPSRNTGRDTSRITGSHK TEQRNADLTDETSRLFVKKT IVVGNVSKYIPPDKREENDQ STHKWMVYVRGSRREPSINH FVKKVWFFLHPSYKPNDLVE VREPPFHLTRRGWGEFPVRV QVHFKDSQNKRIDIIHNLKL DRTYTGLQTLGAETVVDVEL HR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 130-331 of human YEATS2 (NP_060493.3). |
Additional Info
| Function | Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. |
| Protein Name | Yeats Domain-Containing Protein 2 |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-9772755 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Yeats Domain-Containing Protein 2 antibodyAnti-YEATS2 antibodyAnti-KIAA1197 antibody |
Information sourced from Uniprot.org