| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-YEATS2 (130-331) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
YEATS2 |
| Gene ID: |
55689 |
| Uniprot ID: |
YETS2_HUMAN |
| Immunogen Region: |
130-331 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 130-331 of human YEATS2 (NP_060493.3). |
| Immunogen Sequence: |
AETPSANHSESDSLSQHNDF LSDKDNNSNMDIEERLSNNM EQRPSRNTGRDTSRITGSHK TEQRNADLTDETSRLFVKKT IVVGNVSKYIPPDKREENDQ STHKWMVYVRGSRREPSINH FVKKVWFFLHPSYKPNDLVE VREPPFHLTRRGWGEFPVRV QVHFKDSQNKRIDIIHNLKL DRTYTGLQTLGAETVVDVEL HR |
| Function | Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. |
| Protein Name | Yeats Domain-Containing Protein 2 |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-9772755 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Yeats Domain-Containing Protein 2 antibodyAnti-YEATS2 antibodyAnti-KIAA1197 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
