• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using XRN2 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from COS7 cells, using XRN2 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using XRN2 Polyclonal Antibody diluted at 1：1000. Secondary antibody was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-XRN2 antibody (81-130 aa) (STJ96287)

SKU:
STJ96287

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Monkey
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-5 3 exoribonuclease 2 (81-130 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: XRN2
Gene ID: 22803
Uniprot ID: XRN2_HUMAN
Immunogen Region: 81-130 aa
Specificity: XRN2 Polyclonal Antibody detects endogenous levels of XRN2 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human XRN2 at the amino acid range 81-130
Function Possesses 5'->3' exoribonuclease activity. May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites.
Protein Name 5'-3' Exoribonuclease 2
Dhm1-Like Protein
Dhp Protein
Database Links Reactome: R-HSA-390471
Reactome: R-HSA-6791226
Cellular Localisation Nucleus
Nucleolus
Alternative Antibody Names Anti-5'-3' Exoribonuclease 2 antibody
Anti-Dhm1-Like Protein antibody
Anti-Dhp Protein antibody
Anti-XRN2 antibody

Information sourced from Uniprot.org

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