Anti-XPNPEP2 antibody (22-240) (STJ112293)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal XPNPEP2 (22-240) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | XPNPEP2 |
| Gene ID | 7512 |
| Uniprot ID | XPP2_HUMAN |
| Immunogen Region | 22-240 |
| Immunogen Sequence | HTKPVDLGGQDVRNCSTNPP YLPVTVVNTTMSLTALRQQM QTQNLSAYIIPGTDAHMNEY IGQHDERRAWITGFTGSAGT AVVTMKKAAVWTDSRYWTQA ERQMDCNWELHKEVGTTPIV TWLLTEIPAGGRVGFDPFLL SIDTWESYDLALQGSNRQLV SITTNLVDLVWGSERPPVPN QPIYALQEAFTGSTWQEKVS GVRSQMQKHQKVPTAVLLS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 22-240 of human XPNPEP2 (NP_003390.4). |
Additional Info
| Tissue Specificity | Expressed in kidney, lung, heart, placenta, liver, small intestine and colon. No expression in brain, skeletal muscle, pancreas, spleen, thymus, prostate, testis and ovary. |
| Post Translational Modifications | N-glycosylated. |
| Function | Membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. May play a role in the metabolism of the vasodilator bradykinin. |
| Protein Name | Xaa-Pro Aminopeptidase 2Aminoacylproline AminopeptidaseMembrane-Bound Aminopeptidase PMembrane-Bound AppMembrane-Bound AmpMampX-Pro Aminopeptidase 2 |
| Database Links | Reactome: R-HSA-163125 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Antibody Names | Anti-Xaa-Pro Aminopeptidase 2 antibodyAnti-Aminoacylproline Aminopeptidase antibodyAnti-Membrane-Bound Aminopeptidase P antibodyAnti-Membrane-Bound App antibodyAnti-Membrane-Bound Amp antibodyAnti-Mamp antibodyAnti-X-Pro Aminopeptidase 2 antibodyAnti-XPNPEP2 antibody |
Information sourced from Uniprot.org