| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Xanthine dehydrogenase/oxidase is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | XDH |
| Gene ID: | 7498 |
| Uniprot ID: | XDH_HUMAN |
| Specificity: | XDH Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Post Translational Modifications | Subject to partial proteolysis.this alters the enzyme from the dehydrogenase form (D) to the oxidase form (O). Contains sulfhydryl groups that are easily oxidized (in vitro).this alters the enzyme from the dehydrogenase form (D) to the oxidase form (O). |
| Function | Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro). |
| Protein Name | Xanthine Dehydrogenase/Oxidase Includes - Xanthine Dehydrogenase Xd - Xanthine Oxidase Xo Xanthine Oxidoreductase Xor |
| Database Links | Reactome: R-HSA-74259 Reactome: R-HSA-8851680 Reactome: R-HSA-9748787 |
| Cellular Localisation | Cytoplasm Peroxisome Secreted |
| Alternative Antibody Names | Anti-Xanthine Dehydrogenase/Oxidase Includes - Xanthine Dehydrogenase antibody Anti-Xd - Xanthine Oxidase antibody Anti-Xo antibody Anti-Xanthine Oxidoreductase antibody Anti-Xor antibody Anti-XDH antibody Anti-XDHA antibody |
Information sourced from Uniprot.org