| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-XCL1/XCL2 (Internal) is suitable for use in ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000. WB: Preliminary experiments gave an approx 80kDa band in Human Peripheral Blood Mononucleocytes lysates after 0.3µg/ml antibody staining. Please note that currently we cannot find an expla |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | XCL1 |
| Gene ID: | 6375 |
| Uniprot ID: | XCL1_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_002986.1; NP_003166.1 |
| Specificity: | XCL1 and CXL2 are almost identical and therefore this antibody is expected to recognize both proteins. |
| Immunogen Sequence: | RDVVRSMDRKSNTRN |
| Function | Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment. |
| Protein Name | Lymphotactin Atac C Motif Chemokine 1 Cytokine Scm-1 Lymphotaxin Scm-1-Alpha Small-Inducible Cytokine C1 Xc Chemokine Ligand 1 |
| Database Links | Reactome: R-HSA-380108 Reactome: R-HSA-416476 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Lymphotactin antibody Anti-Atac antibody Anti-C Motif Chemokine 1 antibody Anti-Cytokine Scm-1 antibody Anti-Lymphotaxin antibody Anti-Scm-1-Alpha antibody Anti-Small-Inducible Cytokine C1 antibody Anti-Xc Chemokine Ligand 1 antibody Anti-XCL1 antibody Anti-LTN antibody Anti-SCYC1 antibody |
Information sourced from Uniprot.org