| Host: | Rabbit |
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | XCL1 |
| Gene ID: | 6375 |
| Uniprot ID: | XCL1_HUMAN |
| Immunogen Region: | 22-114 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-114 of human XCL1 (NP_002986.1). |
| Immunogen Sequence: | VGSEVSDKRTCVSLTTQRLP VSRIKTYTITEGSLRAVIFI TKRGLKVCADPQATWVRDVV RSMDRKSNTRNNMIQTKPTG TQQSTNTAVTLTG |
| Tissue Specificity | Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine. |
| Function | Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment. |
| Protein Name | LymphotactinAtacC Motif Chemokine 1Cytokine Scm-1LymphotaxinScm-1-AlphaSmall-Inducible Cytokine C1Xc Chemokine Ligand 1 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-416476 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Lymphotactin antibodyAnti-Atac antibodyAnti-C Motif Chemokine 1 antibodyAnti-Cytokine Scm-1 antibodyAnti-Lymphotaxin antibodyAnti-Scm-1-Alpha antibodyAnti-Small-Inducible Cytokine C1 antibodyAnti-Xc Chemokine Ligand 1 antibodyAnti-XCL1 antibodyAnti-LTN antibodyAnti-SCYC1 antibody |
Information sourced from Uniprot.org