Anti-Xanthine Oxidase antibody [R08-2Z6] (STJA0036940)

SKU:
STJA0036940
$184.23 - $388.47
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Host: Rabbit
Applications: WB/IHC-P
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-Xanthine Oxidase for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R08-2Z6
Conjugation: Unconjugated
Isotype: IgG
Formulation: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification: Affinity Chromatography
Dilution Range: WB 1:500-1:1000
IHC 1:50-1:100
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: XDH
Gene ID: 7498
Uniprot ID: XDH_HUMAN
Immunogen: A synthesized peptide derived from human Xanthine Oxidase
Tissue Specificity Detected in milk (at protein level).
Post Translational Modifications Subject to partial proteolysis.this alters the enzyme from the dehydrogenase form (D) to the oxidase form (O). Contains sulfhydryl groups that are easily oxidized (in vitro).this alters the enzyme from the dehydrogenase form (D) to the oxidase form (O).
Function Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro).
Protein Name Xanthine Dehydrogenase/Oxidase Includes - Xanthine Dehydrogenase
Xd - Xanthine Oxidase
Xo
Xanthine Oxidoreductase
Xor
Database Links Reactome: R-HSA-74259
Reactome: R-HSA-8851680
Reactome: R-HSA-9748787
Cellular Localisation Cytoplasm
Peroxisome
Secreted
Alternative Antibody Names Anti-Xanthine Dehydrogenase/Oxidase Includes - Xanthine Dehydrogenase antibody
Anti-Xd - Xanthine Oxidase antibody
Anti-Xo antibody
Anti-Xanthine Oxidoreductase antibody
Anti-Xor antibody
Anti-XDH antibody
Anti-XDHA antibody

Information sourced from Uniprot.org