Anti-WNT3 antibody (161-329 aa) [4F11-H1-F4] (STJA0012869)

Name: Anti-WNT3 antibody (161-329 aa) [4F11-H1-F4] (STJA0012869)
SKU: STJA0012869-100
Price: 281.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostMouse

ConjugationUnconjugated

IsotypeIgG1

ImmunogenPurified recombinant human Wnt3 protein fragments expressed in E.coli.

STJA0012869-100

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Short Description	Mouse monoclonal anti-Wnt3 (161-329 aa) for use in WB in Transfected samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB
Host	Mouse
Reactivity	Transfected
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	4F11-H1-F4
Isotype	IgG1
Conjugation	Unconjugated
Concentration	3 mg/mL
Purification	Affinity Purified
Dilution Range	WB 1:500-1:1000
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage Instruction	Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.

Gene Symbol	WNT3
Gene ID	7473
Uniprot ID	WNT3_HUMAN
Immunogen	Purified recombinant human Wnt3 protein fragments expressed in E.coli.
Immunogen Region	161-329 aa

Post Translational Modifications	Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
Function	Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal gastrulation, formation of the primitive streak, and for the formation of the mesoderm during early embryogenesis. Required for normal formation of the apical ectodermal ridge. Required for normal embryonic development, and especially for limb development.
Protein Name	Proto-Oncogene Wnt-3 Proto-Oncogene Int-4 Homolog
Database Links	Reactome: R-HSA-201681 Reactome: R-HSA-3238698 Reactome: R-HSA-373080
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix
Alternative Antibody Names	Anti-Proto-Oncogene Wnt-3 antibody Anti-Proto-Oncogene Int-4 Homolog antibody Anti-WNT3 antibody Anti-INT4 antibody

Information sourced from Uniprot.org