Anti-Wnt2 antibody [R01-5I9] (STJA0035866)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human WNT2
General Information
| Short Description | Rabbit monoclonal anti-Wnt2 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R01-5I9 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | WNT2 |
| Gene ID | 7472 |
| Uniprot ID | WNT2_HUMAN |
| Immunogen | A synthesized peptide derived from human WNT2 |
Additional Info
| Tissue Specificity | Expressed in brain in the thalamus, in fetal and adult lung and in placenta. |
| Post Translational Modifications | Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition. |
| Function | Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Functions as a upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons. |
| Protein Name | Protein Wnt-2Int-1-Like Protein 1Int-1-Related ProteinIrp |
| Database Links | Reactome: R-HSA-3238698Reactome: R-HSA-373080 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Protein Wnt-2 antibodyAnti-Int-1-Like Protein 1 antibodyAnti-Int-1-Related Protein antibodyAnti-Irp antibodyAnti-WNT2 antibodyAnti-INT1L1 antibodyAnti-IRP antibody |
Information sourced from Uniprot.org