Anti-WNT1 antibody [10C8] (STJ98451)

Name: Anti-WNT1 antibody [10C8] (STJ98451)
SKU: STJ98451
Availability: InStock

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SPECIFICATIONS

ClonalityMonoclonal

HostMouse

ConjugationUnconjugated

IsotypeIgG1

ImmunogenPurified recombinant fragment of Wnt-1 expressed in E. Coli.

STJ98451

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Short Description	Mouse monoclonal anti-Proto-oncogene Wnt-1 for use in WB, IHC, IF, FC and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC/IF/FC/ELISA
Host	Mouse
Reactivity	Human/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	10C8
Isotype	IgG1
Conjugation	Unconjugated
Purification	Affinity purification
Dilution Range	WB 1:500-1:2000 IHC 1:200-1:1000 IF 1:200-1:1000 FC 1:200-1:400 ELISA 1:10000
Formulation	Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	WNT1
Gene ID	7471
Uniprot ID	WNT1_HUMAN
Immunogen	Purified recombinant fragment of Wnt-1 expressed in E. Coli.
Specificity	Wnt-1 Monoclonal Antibody detects endogenous levels of Wnt-1 protein.

Function	Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Plays an essential role in the development of the embryonic brain and central nervous system (CNS). Has a role in osteoblast function, bone development and bone homeostasis.
Protein Name	Proto-Oncogene Wnt-1 Proto-Oncogene Int-1 Homolog
Database Links	Reactome: R-HSA-201681 Reactome: R-HSA-3238698 Reactome: R-HSA-373080 Reactome: R-HSA-381340 Reactome: R-HSA-4086400 Reactome: R-HSA-4641262
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix
Alternative Antibody Names	Anti-Proto-Oncogene Wnt-1 antibody Anti-Proto-Oncogene Int-1 Homolog antibody Anti-WNT1 antibody Anti-INT1 antibody

Information sourced from Uniprot.org