Host: |
Mouse |
Applications: |
WB/IHC/IF/FC/ELISA |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-Proto-oncogene Wnt-1 is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry and ELISA research applications. |
Clonality: |
Monoclonal |
Clone ID: |
10C8 |
Conjugation: |
Unconjugated |
Isotype: |
IgG1 |
Formulation: |
Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IHC 1:200-1:1000IF 1:200-1:1000FC 1:200-1:400ELISA 1:10000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
WNT1 |
Gene ID: |
7471 |
Uniprot ID: |
WNT1_HUMAN |
Specificity: |
Wnt-1 Monoclonal Antibody detects endogenous levels of Wnt-1 protein. |
Immunogen: |
Purified recombinant fragment of Wnt-1 expressed in E. Coli. |
Function | Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Plays an essential role in the development of the embryonic brain and central nervous system (CNS). Has a role in osteoblast function, bone development and bone homeostasis. |
Protein Name | Proto-Oncogene Wnt-1Proto-Oncogene Int-1 Homolog |
Database Links | Reactome: R-HSA-201681Reactome: R-HSA-3238698Reactome: R-HSA-373080Reactome: R-HSA-381340Reactome: R-HSA-4086400Reactome: R-HSA-4641262 |
Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
Alternative Antibody Names | Anti-Proto-Oncogene Wnt-1 antibodyAnti-Proto-Oncogene Int-1 Homolog antibodyAnti-WNT1 antibodyAnti-INT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance