| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC |
| Reactivity: |
Human/Mouse/Rat/Dog/Cow |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-WHIP/WRNIP1 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
IHC-Recommended concentration, 4-6µg/mlELISA-antibody detection limit dilution 1:32000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
WRNIP1 |
| Gene ID: |
56897 |
| Uniprot ID: |
WRIP1_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_064520.2; NP_569079.1 |
| Specificity: |
This antibody is expected to recognise isoform 1 (NP_064520.2) and isoform 2 (NP_569079.1). |
| Immunogen Sequence: |
EELRGVDFFKQRRC |
| Post Translational Modifications | Sumoylated with SUMO1 and SUMO2/3. |
| Function | Functions as a modulator of initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. In the presence of ATP, stimulation of DNA polymerase delta-mediated DNA synthesis is decreased. Also plays a role in the innate immune defense against viruses. Stabilizes the RIGI dsRNA interaction and promotes RIGI 'Lys-63'-linked polyubiquitination. In turn, RIGI transmits the signal through mitochondrial MAVS. |
| Protein Name | Atpase Wrnip1Werner Helicase-Interacting Protein 1 |
| Cellular Localisation | NucleusCytoplasmColocalizes With Wrn In Granular Structures In The Nucleus |
| Alternative Antibody Names | Anti-Atpase Wrnip1 antibodyAnti-Werner Helicase-Interacting Protein 1 antibodyAnti-WRNIP1 antibodyAnti-WHIP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
